Publications

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(2020). Conditional Power and Friends: The Why and How of (Un)planned, Unblinded Sample Size Recalculations in Confirmatory Trials. Submitted.

arxiv

(2020). Principal Stratum Strategy: Potential Role in Drug Development. Submitted.

arxiv markdown github

(2020). Survival analysis for AdVerse events with VarYing follow-up times (SAVVY) - comparison of adverse event risks in randomized controlled trials. Submitted. *The first two authors contributed equally to this paper.

Project arxiv markdown github

(2020). Survival analysis for AdVerse events with VarYing follow-up times (SAVVY) - estimation of adverse event risks. Submitted.

Project arxiv markdown github

(2020). A review of Bayesian perspectives on sample size derivation for confirmatory trials. Submitted.

arxiv Code on github Shiny app for sample size calculation

(2020). Estimands for Overall Survival in Clinical Trials with Treatment Switching. Submitted.

(2020). Estimands in Hematology Trials. Under revision.

arxiv

(2020). Survival analysis for AdVerse events with VarYing follow-up times (SAVVY): Rationale and statistical concept of a meta-analytic study. Biom. J., to appear.

Project arxiv

(2020). Assessing the impact of COVID-19 on the objective and analysis of oncology clinical trials - application of the estimand framework. Statistics in Biopharmaceutical Research, to appear. *The first four authors contributed equally to this paper.

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(2019). Joint modelling of progression-free and overall survival and computation of correlation measures. Stat. Med., 38, 4270-4289.

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(2019). A multistate model for early decision making in oncology. Biom. J., 62(3), 550-567.

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(2016). Comparison of design strategies for a three-arm clinical trial with time-to-event endpoint: power, time-to-analysis, and operational aspects. Biom. J., 58(6), 1295-1310.

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(2016). Comparison of different clinical development plans for confirmatory subpopulation selection. Contemp. Clin. Trials, 47, 78-84.

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(2014). Maximum-Likelihood Estimation of a Log-Concave Density based on Censored Data. Electron. J. Stat., 8, 1405-1437.

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(2013). Asymptotics of the discrete log-concave maximum likelihood estimator and related applications. J. R. Stat. Soc. Ser. B Stat. Methodol., 75(4), 769-790.

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(2011). logcondens: Computations Related to Univariate Log-Concave Density Estimation. Journal of Statistical Software, 39(6), 1-28.

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(2010). A score regression approach to assess calibration of probabilistic predictions. Biometrics, 66(4), 1295-1305.

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(2010). Least Squares estimation of two ordered monotone regression curves. J. Nonparametr. Stat., 22(8), 1019-1037.

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(2009). reporttools: R Functions to Generate LaTeX Tables of Descriptive Statistics. Journal of Statistical Software, Code Snippets, (31), 1.

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(2009). Smooth tail index estimation. J. Statist. Comput. Simulation, (79), 1155-1167.

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(2009). Limit Distribution Theory for Maximum Likelihood Estimation of a Log-Concave Density. Ann. Statist., (37), 1299-1331.

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(2008). On the max-domain of attraction of distributions with log-concave densities. Statist. Probab. Lett., (78), 12, 1440-1444.

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(2008). A second Marshall inequality in convex estimation. Statist. Probab. Lett., 78(2), 118-126.

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(2001). Eintrittsraten und Austrittswahrscheinlichkeiten EVK 2000. Mitteilungen der Schweizerischen Aktuarvereinigung, 2001(1), 49-70.

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