2020/06: A toolbox for innovative confirmatory trial designs

Four 2h modules delivered to all of Roche biostatistics with the following content:

  • Efficient use of futility and efficacy interim analyses in group-sequential designs
  • Intro to adaptive trial designs and (blinded and unblinded) sample size re-calculation
  • Adaptive designs with multiplicity and adaptive enrichment trials
  • Multi-arm trials and time-to-event endpoints

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